Shedding light over COVID-19 susceptibility and severity
“One of the most remarkable features of SARS-CoV-2 infection is the variation in consequence ranging from asymptomatic to life-threatening” state the authors of the majestic …
Providing access to COVID-19 data: One year later
EGA joins COVID-19 response efforts On 11 March 2020 the World Health Organization declared the novel coronavirus outbreak a global pandemic. Four months later, the …
The last addition to the list of clonal evolution studies in the EGA
Tumours of different types may arise from a single cell with at least one malignant mutation. Accumulation of subsequent hits generates lineages of cells with …
Advancing fast in the analysis of circulating tumour DNA
The physiological death of human normal haematopoietic cells releases DNA fragments into the bloodstream. This is called cell-free DNA and it is indeed broken DNA …
Finding the way towards the eradication of therapy-related myeloid neoplasms
Therapy-related neoplasms are directly caused by the drugs used to eradicate a previous cancer. It is well known that a subset of drugs designed to …
20 years after the first human genome release, where are we heading?
On February 2021 we celebrated the 20th anniversary of the release of the first human genome. That has been a milestone output of the Human …
Data Upcycling, powered by EGA
At EGA we stand for efficient and secure sharing of human genomic data. Data upcycling can create some virtuous paths with an amazing potential to …
Gut microbiome dynamics unravelled with metagenomics sequencing
It has been already several years since we discovered that microbial therapeutics like Faecal Microbiota Transplantation can be used to treat Clostridium difficile infection (CDI) and Inflammatory …
The Federated EGA network
Generation of human genomic and phenotypic data is increasing at an exponential rate and with it, the need for efficient data management and secure sharing. …
Reading about genomic analysis of Pan-Neuroblastoma
(A scratchy summary about the huge work from Samuel W. Brady and colleagues, published in Nature Communications this October 2020) There are virtually no research …