Browse Dataset Files
Assessment of genetic and epigenetic variation in human IPS cells
|EGAD00001000798||Illumina HiSeq 2000,Illumina HiSeq 2500,Illumina MiSeq||28|
In order to progress human induced pluripotent stem cells (hiPSCs) towards the clinic, several outstanding questions must be addressed. It is possible to reprogram different somatic cell types into hiPSCs but it is unclear whether some cell types carry through fewer mutations through reprogramming (either due to mutations present in the primary cells, or mutations accumulated during reprogramming). Through in depth analysis of hiPSCs generated from different somatic cells, it will be possible to assess the variation in genetic stability of different cell types.