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Comprehensive single cell study of lung adenocarcinoma from early to metastatic stages

Dataset ID Technology Samples
EGAD00001005054 Illumina HiSeq 2500 80

Dataset Description

We performed single cell RNA sequencing (scRNA-seq) for 208,506 cells derived from 58 lung adenocarcinomas from 44 patients, which covers primary tumour, lymph node and brain metastases, and pleural effusion in addition to normal lung tissues and lymph nodes. The extensive single cell profiles depicted a complex cellular atlas and dynamics during lung adenocarcinoma progression which includes cancer, stromal, and immune cells in the surrounding tumor microenvironments.

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