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Pre-clinical evolution of haematological malignancies TGS

Dataset ID Technology Samples
EGAD00001006424 Illumina HiSeq 2500,Illumina HiSeq 4000 48

Dataset Description

Leukaemia and related blood cancers occur due to genetic changes that typically accumulate over many years. This study will employ targeted next-generation sequencing to retrace the preclinical evolution of several types of haematological malignancy. Investigating the progression of the earliest pre-malignant ancestral clones promises to offer valuable insights into early leukaemia evolution and therapeutic vulnerabilities of leukaemia stem cells.