Regions of common inter-individual DNA methylation differences in human monocytes.
|Study ID||Alternative Stable ID||Type|
Based on whole genome bisulfite sequencing of five human monocytes from unrelated individuals, we have identified regions of common inter-individual DNA methylation differences, where methylation is inversely correlated with active histone marks, but not with the expression of the associated genes. Genome-wide association studies in 1128 individuals show that allelic DNA methylation is caused by genetic variation in cis. At some loci, DNA methylation appears to be affected also by genetic variation in trans.
Study Datasets 2 dataset.
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|EGAD00001003259||Regions of common inter-individual DNA methylation differences in human monocytes – potential function and genetic basis WGBS Data of Samples: 43_Hm03_BlMo_Ct, 43_Hm02_BlMo_Ct, 43_Hm05_BlMo_Ct, 43_Hm01_BlMo_Ct For details about sequencing or sample metadata check http://deep.dkfz.de/||Illumina HiSeq 2000||4|
|EGAD00010001294||Methylation data using 450K||Illumina 450k||1128|
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Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function.
Epigenetics Chromatin 10:2017 37