Profiling of Peritoneal Metastases from Gastric Adenocarcinoma Identified Molecular Subtypes
|Study ID||Alternative Stable ID||Type|
Peritoneal carcinomatosis (PC) occurs frequently in gastric adenocarcinoma (GAC) patients and confers poor prognosis. Multiplex profiling of primary GACs has been insightful but the underpinnings of PC’s development/progression remain largely unknown. Here we characterized exome/transcriptome/immune landscapes of PC cells from 43 patients.
Study Datasets 2 dataset.
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|EGAD00001004364||Whole-exome sequencing (WES) was performed on a total of 34 PC specimens, with 15 cases having matched gDNAs extracted from blood.||Illumina HiSeq 4000||49|
|EGAD00001004365||Whole transcriptome sequencing (RNA-seq) was performed on 39 PC specimens. Among them, 21 specimens also had WES data.||Illumina HiSeq 4000||39|
Who archives the data?
Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response.
Gut 69:2020 18-31