Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases
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Through whole-genome methylation analysis of plasma samples from patients with nasopharyngeal carcinoma (NPC), EBV-associated lymphoma and infectious mononucleosis, we demonstrate that EBV DNA methylation profiles exhibit a disease-associated pattern. Such observation implies significant potentials in the development of methylation analysis of plasma EBV DNA for NPC diagnostics.
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Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases.
Nat Commun 10:2019 3256