International consensus definition of DNA methylation subgroups in juvenile myelomonocytic leukemia
|Study ID||Alternative Stable ID||Type|
Known clinical and genetic markers have limitations in predicting disease course and outcome in juvenile myelomonocytic leukemia (JMML). DNA methylation (DNAme) patterns in JMML have correlated with outcome across multiple studies, suggesting it as a biomarker to improve patient stratification. However, standardized approaches to classify JMML based on DNAme patterns are lacking. We therefore sought to define an international consensus for DNAme subgroups in JMML and develop classification methods for clinical implementation.
Study Datasets 3 dataset.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
|EGAD00010001998||DNA methylation analysis of JMML patients from Europe, Japan and USA using EPIC arrays||Infinium HumanMethylation450K and EPIC BeadChip||32|
|EGAD00010001999||DNA methylation analysis of JMML patients from Europe, Japan and USA using 450k arrays||Infinium HumanMethylation450K and EPIC BeadChip||292|
|EGAD00010002000||DNA methylation analysis of JMML patients from Europe, Japan and USA using EPIC arrays||Infinium HumanMethylation450K and EPIC BeadChip||47|
Who archives the data?
International Consensus Definition of DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia.
Clin Cancer Res 27:2021 158-168