Study

Immunological hallmarks for clinical response to BCG in bladder cancer

Study ID Alternative Stable ID Type
EGAS00001004764 Other

Study Description

Intravesical Bacillus Calmette-Guerin (BCG) is an effective immunotherapy for non-muscle invasive bladder cancer (NMIBC). However, recurrence and progression remain frequent warranting deeper insights into its mechanism. We herein comprehensively profiled blood and tissues obtained from NMIBC patients before, during and after BCG treatment using cytometry by time-of-flight (CyTOF) and RNA sequencing to identify the key immune subsets crucial for anti-tumour activity.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
EGAD00001006634 We have in total 16 files, technical duplicates of 8 unique samples from Pre and Post BCG samples collected from four non muscle invasive bladder cancer patients. These are bulk RNAseq samples generated by high-throughput sequencing platform. Illumina HiSeq 4000 16

Who archives the data?

Publications

Publications Citations
Immunological Hallmarks for Clinical Response to BCG in Bladder Cancer.
Front Immunol 11:2020 615091
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