Study
Temporal and Clonal Progression in Pediatric Ependymoma
Study ID | Alternative Stable ID | Type |
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phs001461 | Longitudinal |
Study Description
Whole genome and exome-based DNA sequencing of germline and tumor specimens from serial samples of a single patient's ependymoma. The findings reveal the extent to which treatment with radiation and chemotherapies resulted in the diversification of the tumor subclonal architecture and shaped the neo-antigen landscape, and provide new insights into possible molecular mechanisms of oncogenesis, treatment response and recurrence.
Archive | Link Archive Accession |
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dbGaP | phs001461 |
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