NHLBI TOPMed: Pulmonary Hypertension and the Hypoxic Response in SCD (PUSH)

Study ID Alternative Stable ID Type
phs001682 Case-Control

Study Description

During Visit One, the PUSH Study will perform echocardiography on 600 children and adolescent with patients with SCD and 100 control children and adolescents at three Field Centers, namely Howard University, Children's National Medical Center and University of Michigan. Patients or their parents will be approached and asked to give informed consent. If they appear to have difficulty reading, reading of the consent will be offered. Patients or their parents not appearing to comprehend the consent will not be eligible. As a part of this visit, each participant or parent will sign informed consent, complete a Participant Contact Information Form, complete a Medical History Form, undergo physical examination with completion of a Physical Examination Form and have blood drawn. Each participant must have echocardiography performed with measurement of Tricuspid Regurgitant Jet Velocity (TRV). In addition attempts will be made 1) to perform a six-minute walk test, 2) to collect information from a recent (within six months) Transcranial Doppler Study (TCD) or to perform TCD, and 3) ... (Show More)

Archive Link Archive Accession
dbGaP phs001682

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