The European Genome-phenome Archive (EGA) is a service for permanent archiving and sharing of all types of personally identifiable genetic and phenotypic data resulting from biomedical research projects.
  • Latest studies

    Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening. – 2019-05-16

    To systematically investigate the role of fusions in tumour cell fitness, we utilized RNA-sequencing data from 1011 human cancer cell lines to functionally link 8354 fusion events with ge Read more

     Study 1 / 4

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  • Latest studies

    Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus. – 2019-05-15

    Systemic lupus erythematosus (SLE) is an autoimmune disease, characterised by increased expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards females. Read more

     Study 2 / 4

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  • Latest studies

    Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array. – 2019-05-14

    BACKGROUND:There has been a steady increase in the number of studies aiming to identify DNA methylation differences associated with complex phenotypes. Many of the challenges of epigeneti Read more

     Study 3 / 4

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  • Latest studies

    Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma. – 2019-03-29

    Burkitt lymphoma (BL) is the most common B-cell lymphoma in children. Within the International Cancer Genome Consortium (ICGC), we performed whole genome and transcriptome sequencing of 3 Read more

     Study 4 / 4

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