DAC

University of Heidelberg MUO

Dac ID Contact Person Email Access Information
EGAC00001000470 Stefan Duensing stefan [dot] duensing [at] med [dot] uni-heidelberg [dot] de

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001002067 Renal cell carcinoma (RCC) is a genomically heterogeneous tumor. In the present project, the question whether intratumoral heterogeneity follows a zonal pattern indicating spatial niches was addressed. Whole exome sequencing of 16 paired samples from tumor periphery and center revealed a number of region-specific functional SNVs and Indels. Therefore, RCCs are not composed of evenly admixed tumor cells but show topological differences in their clonal composition. Illumina HiSeq 2500; 16