DAC for Melanoma Exome Dataset for Identification of Mutated Epitopes

Prof. Dr. Angela Krackhardt
angela.krackhardt@tum.de

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Dataset ID	Description	Technology	Samples
EGAD00001002731	whole exome sequencing of tumor- as well as PBMC-derived DNA of five melanoma patients for identification of naturally presented patient-specific neoepitopes	Illumina HiSeq 2000	10
EGAD50000000854	Specific in vitro stimulation of patient-derived PBMC with the neoantigens SYTL4-S363F and KIF2C-P13L was followed by enriching for CD137+ activated T cells. Restimulated T cells as well as an unstimulated patient PBMC sample from the same time point were used for scRNA-Seq/scTCR-Seq.	Illumina NovaSeq 6000	4