Epigenetic dysregulation in autism spectrum disorder

Dac ID Contact Person Email Access Information
EGAC00001000547 Daniel H. Geschwind dhg [at] mednet [dot] ucla [dot] edu

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001002725 Autism spectrum disorder (ASD) is a collection of neuro-developmental disorders characterized by deficits in social interaction and social communication, along with restricted and repetitive behaviour patterns. we globally interrogated the histone acetylomes of enhancers in a large cohort of ASD and control samples by analyzing tissue from three brain regions postmortem: prefrontal cortex (PFC), temporal cortex (TC) and cerebellum (CB). H3K27ac was selected as the representative acetylation mark and 288 ChIP-seq were performed on these postmortem samples. Illumina HiSeq 2000;ILLUMINA 291