Epigenetic dysregulation in autism spectrum disorder

Daniel H. Geschwind
dhg@mednet.ucla.edu

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Dataset ID	Description	Technology	Samples
EGAD00001002725	Autism spectrum disorder (ASD) is a collection of neuro-developmental disorders characterized by deficits in social interaction and social communication, along with restricted and repetitive behaviour patterns. we globally interrogated the histone acetylomes of enhancers in a large cohort of ASD and control samples by analyzing tissue from three brain regions postmortem: prefrontal cortex (PFC), temporal cortex (TC) and cerebellum (CB). H3K27ac was selected as the representative acetylation mark and 288 ChIP-seq were performed on these postmortem samples.	Illumina HiSeq 2000	291