DAC for patient-derived cell line samples

Dac ID Contact Person Email Access Information
EGAC00001000594 Christian Conrad christian [dot] conrad [at] bihealth [dot] de No additional information is available

This DAC controls 5 datasets:

Dataset ID Description Technology Samples
EGAD00001003146 We performed whole genome sequencing of nine OC patient-derived cell lines and one normal cell line (HOSEpiC) to analyze if the cell lines harbor OC-typical genomic aberrations absent in normal cells and to relate genomic features to drug sensitivities. 10
EGAD00001004131 Pheno-seq is a new approach that integrates high-throughput imaging and transcriptomic profiling of clonal spheroids/organoids to dissect functional tumor cell heterogeneity in 3D cell culture systems. The method is based on the iCELL8 technology (TakaraBio) that uses barcoded nanowells and a micro-solenoid valve dispenser. The CRC_spheroid dataset contains demultiplexed RNA-sequencing profiles (FASTQ file format, NextSeq 500) of 95 clonal tumor spheroids derived from a patient with colorectal cancer. NextSeq 500 1
EGAD00001005315 NA NextSeq 500 9
EGAD00001006185 ALI culture bronchial cells and alveolar lung surgical resection scRNA-Seq Illumina HiSeq 4000 16
EGAD00001006448 NA NextSeq 500 25