High Altitude Pulmonary Hypertension

Dac ID Contact Person Email Access Information
EGAC00001000994 Prof Haddad ghaddad [at] ucsd [dot] edu No additional information is available

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001004308 The Central Asian Kyrgyz highland population provides a unique opportunity to address genetic diversity and understand the genetic mechanisms underlying hypoxia-induced high altitude pulmonary hypertension (HAPH). While a significant fraction of the population is unaffected, there are susceptible individuals who display HAPH in the absence of any lung, cardiac or hematologic disease. We report herein the analysis of the whole genome sequencing of healthy individuals compared with HAPH patients and other controls. In this study, 34 male individuals from Central Asian Kyrgyz highland are sequenced with Illumina HiSeq 2000 with mean-coverage of 30X. Illumina HiSeq 2000 34