Data Access Committee LUMC-KFT pharmacogenetics

Dac ID Contact Person Email Access Information
EGAC00001001486 Jesse Swen j [dot] j [dot] swen [at] lumc [dot] nl No additional information is available

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001005972 Dataset contains CYP2D6 sequencing data of 566 individuals who used tamoxifen as adjuvant breast cancer therapy. Phenotype data consists of the ratio between the metabolites endoxifen and desmethyltamoxifen (Metabolic ratio (MR)) as a proxy for CYP2D6 enzyme activity. Each sample is linked to one bam-file containing the CYP2D6 sequence. PacBio RS II 566