Detection of ctDNA in Plasma of Patients with Clinically Localised Prostate Cancer is Associated with Rapid Disease Progression

Dac ID Contact Person Email Access Information
EGAC00001001718 Niall Corcoran con [at] unimelb [dot] edu [dot] au No additional information is available

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001006369 Whole genome sequencing of tumour-normal pairs in eight patients with clinically localised disease undergoing prostatectomy. A bespoke DNA capture and amplification panel against the highest prevalence, highest confidence aberrations for each individual was designed and used to interrogate ctDNA isolated from plasma prospectively obtained pre- and post- (24 hours and 6 weeks) surgery. Tagged-amplicon deep sequencing (TAm-Seq) across the TP53 gene in ctDNA in a cohort of 189 individuals. 224