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RiMod-FTD Data Access Commitee

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Anna-Lena Hilje
anna-lena.hillje@dzne.de

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This DAC controls 7 datasets

Dataset ID	Description	Technology	Samples
EGAD00001006842	Microglia were derived from iPSCs and treated with mimics and inhibitors of the miRNAs hsa-miR-150-5p, hsa-miR-193a-3p and hsa-miR-19b-3p. RNA-sequencing was then performed to examine the effects of up- and down-regulation of the respective miRNAs.	NextSeq 550	30
EGAD00001006843	CAGE-sequencing was performed on frontal post-mortem human brain tissue of patients with FTD caused by mutations in GRN, MAPT or C9orf72 and healthy controls.	Illumina HiSeq 2000	57
EGAD00001006844	iPSC-derived neurons were treated with mimics and inhibitors of the miRNAs miR-150-5p, hsa-mir-193a-3p and hsa-miR-19b-3p. RNA-sequencing was then performed to examine the effects of miRNA up-regulation and inhibition.	NextSeq 550	15
EGAD00001006845	This dataset contains smRNA-seq data from human post-mortem brain tissue of the frontal lobe of patients with FTD and healthy controls. These samples depict the data generated at the DZNE Göttingen and should be used together with the data generated at the DZNE Tübingen.	NextSeq 550	33
EGAD00001006846	This dataset contains smRNA-seq data from post-mortem human brain tissue of the frontal lobe of patients with FTD and healthy controls. The smRNA-sequencing was done in two parts, this dataset depicts the data generated at the DZNE Tübingen.	NextSeq 550	9
EGAD00001008014	RNA-sequencing dataset of post-mortem human brain tissue of FTD patients with mutations in GRN, MAPT and C9orf72 and healthy controls.	Illumina HiSeq 2500 NextSeq 550	47
EGAD00010002055	Illumina EPIC methylation array of frontal lobe tissue from post-mortem human brains of the RiMod-FTD project	Illumina Infinium MethylationEPIC BeadChip	47