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DACs
EGAC00001002199
Prof. Dr. Markus Heim
Contact Information
Markus Heim
markus.heim@unibas.ch
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This DAC controls 3 datasets
Dataset ID
Description
Technology
Samples
EGAD00001007820
RNAseq of liver organoids with a dG genotype (B20, nt115, U15) and with a TT genotype (nt5, U16, U19) was performed, which was used to study the impact of IFNλ4 on the cellular response to Sendai viral infection.
NextSeq 550
18
EGAD50000000060
We aimed to identify somatic mutations and transcriptional differences that could explain the resistance to Doxorubicin. This dataset includes RNA-Seq of HCC biopsies and Organoids and WES of Organoids.
Illumina HiSeq 2500
Illumina NovaSeq 6000
unspecified
52
EGAD50000001591
We conducted a nested case–control study within a prospective liver biopsy biobank at the University Hospital Basel. Patients with chronic hepatitis C (CHC) who developed hepatocellular carcinoma (HCC) during follow-up (index cases, CHC-HCC) were identified and 1:2 propensity score-matched to CHC controls without HCC (controls, CHC-nonHCC). Matching included clinical, demographic, and virological risk factors for HCC. Liver biopsies were analyzed using RNA and whole-exome sequencing.
Illumina HiSeq 2500
Illumina NovaSeq 6000
139