DAC

Data access committee for the ADJUVANT biomarker study

Dac ID Contact Person Email Access Information
EGAC00001002333 Yi-Long Wu syylwu [at] live [dot] cn No additional information is available

This DAC controls 1 dataset:

Dataset ID Description Technology Samples
EGAD00001008157 This dataset contains targeted sequencing data of 204 surgical samples from resected NSCLC. Genomic profiling identifies five predictive biomarkers, which is then integrated into the Multiple-gene INdex to Evaluate the Relative benefit of Various Adjuvant therapies (MINERVA) score. The MINERVA score categorizes patients into three subgroups with relative disease-free survival and overall survival benefits from either adjuvant gefitinib or chemotherapy. This study demonstrates that predictive genomic signatures could potentially stratify resected EGFR-mutant NSCLC patients and provide precise guidance towards future personalized adjuvant therapy. 204