BipEx_Timpson_Bristol

Mr Laurie Fabian
laurie.fabian@bristol.ac.uk

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Dataset ID	Description	Technology	Samples
EGAD50000000716	These data were generated as part of a collaboration between University of Bristol, UK and the Stanley Center at the Broad Institute. This project sequenced and analysed the whole exomes of 2969 samples from the Avon Longitudinal Study of Parents and Children (ALSPAC). ALSPAC is a population-based pregnancy cohort with participants acting as ‘controls’ for this project. Genomic DNA from each sample was sequenced to a mean depth of 20x. The exome used Twist capture and samples were sequenced on Illumina NovaSeq 6000 machines producing CRAM files. ALSPAC recruited pregnant women in the Avon County of south-west England between 1991 and 1992. Of the 15,447 pregnancies, 14,901 children were alive at 1 year of age. DNA was extracted from child blood samples taken between ages 7 and 24.	Illumina NovaSeq 6000	2969