Human Heart Data Access Committee

Dr Suvi Linna-Kuosmanen
suvi.linna-kuosmanen@uef.fi

Request Access

Dataset ID	Description	Technology	Samples
EGAD50000000927	This dataset includes single-nuclei RNA sequencing (snRNA-seq) and spatial transcriptomics data from biopsies of the right atrial appendage and pericardial fluid, collected during open-heart surgeries. The samples represent various clinical contexts, including control, ischemic heart disease, heart failure, and myocardial infarction. For each biopsy, nuclei were isolated, and RNA sequencing libraries were prepared using the 10x Genomics Chromium v3 platform. Additionally, spatial transcriptomics was performed on the heart samples. The dataset provides raw sequencing data, which includes fastq files generated from these libraries, offering valuable insights into the cellular composition of heart tissues and associated fluids across different disease states.	Illumina NovaSeq 6000 NextSeq 500	81