PCF SELECT data on liquid biopsy samples from 3 clinical studies on prostate cancer patients

Dr Klas D P Wetterskog
d.wetterskog@ucl.ac.uk

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Dataset ID	Description	Technology	Samples
EGAD50000001840	Sequencing data from mCRPC patients receiving cabazitaxel. Targeted sequencing data of prostate cancer relevant genes using the PCF-SELECT capture panel. cfDNA from baseline, on-treatment and progression samples taken on cabazitaxel were sequenced as well as patient match WBC DNA	Illumina NovaSeq 6000	348
EGAD50000001960	Sequencing data from newly diagnosed high emtastatic burder prostate cancer patients receiving an AR pathway inhibitor (ARPI) or docetaxel. Targeted sequencing data of prostate cancer relevant genes using the PCF-SELECT capture panel. cfDNA from PreADT, baseline, on-treatment (Cycle1 to 6) taken on ARPI or Docetaxel were sequenced as well as patient-matched WBC DNA	Illumina NovaSeq 6000	646
EGAD50000003089	Targeted sequencing using the PCF-SELECT capture panel and the KAPA Hypercap workflow on DNA extracted from liquid biopsies to test if ctDNA detection in pretreatment samples associates with worse outcome to stereotactic body radiotherapy in oligoprogressing metastatic castration-resistant prostate cancer patients.	Illumina NovaSeq 6000	219