GeoMx digital spatial profiling of NGS mRNA expression in pre-treatment biopsies from patients.

Dr Laura Soucek
lsoucek@vhio.net

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Dataset ID	Description	Technology	Samples
EGAD50000001932	This dataset contains GeoMx digital spatial profiling (DSP) data from 12 FFPE pre-treatment biopsies of metastatic HR-altered breast cancer patients subsequently treated with PARP inhibitors (Olaparib or Talazoparib). Samples were collected from primary breast tumors (n=7) and metastatic sites including lymph nodes (n=2), bone (n=2), and brain (n=1). Tissue sections were stained for pan-cytokeratin (PANCK) to selectively profile tumor cells, with NGS-based transcriptome data generated for both PANCK+ and PANCK- regions. The dataset includes raw data files (176 fastq files) along with clinical annotations.	NextSeq 2000	13