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Profiling of 27 type 2 diabetes GWAS loci using next-generation (NG) capture C in a human beta-cell model
Most type 2 diabetes association signals are due to variants that impact gene regulation but identifying the genes they impact is challenging. We generated interaction profiles at 27 T2D GWAS loci using next-generation (NG) capture C (6 replicates) in the human beta-cell model, EndoC-betaH1, along with chromatin accessibility profiling using ATAC-Seq (9 replicates).
- DAC: EGAC00001002602
- Technology: NextSeq 500