About file location

As the EGA is co-managed by the EMBL-EBI and CRG, files could be located in the UK and/or Spain, as indicated by their respective flags.

Alternatively, files could be located in one of the international Federated EGA nodes, as indicated next to the node's flag.
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ASCENT diagnosis PBMC single-cell RNA and TCR sequencing

This controlled-access dataset contains single-cell gene expression and T cell receptor V(D)J sequencing data from diagnosis-timepoint peripheral blood mononuclear cell samples from five ASCENT participants. Each participant is represented by paired 10x Genomics GEX and TCR libraries generated from the same PBMC aliquot, giving five GEX and five TCR sequencing runs. The dataset comprises encrypted paired-end Illumina FASTQ files.

DUO:0000007
version: 2021-02-23

disease specific research

This data use permission indicates that use is allowed provided it is related to the specified disease.

ModifiersMONDO:0008903 lung cancer

DUO:0000011
version: 2021-02-23

population origins or ancestry research only

This data use permission indicates that use of the data is limited to the study of population origins or ancestry.

DUO:0000012
version: 2021-02-23

research specific restrictions

This data use modifier indicates that use is limited to studies of a certain research type.

DUO:0000015
version: 2021-02-23

no general methods research

This data use modifier indicates that use does not allow methods development research (e.g., development of software or algorithms).

DUO:0000016
version: 2021-02-23

genetic studies only

This data use modifier indicates that use is limited to genetic studies only (i.e., studies that include genotype research alone or both genotype and phenotype research, but not phenotype research exclusively)

DUO:0000018
version: 2021-02-23

not for profit, non commercial use only

This data use modifier indicates that use of the data is limited to not-for-profit organizations and not-for-profit use, non-commercial use.

DUO:0000019
version: 2021-02-23

publication required

This data use modifier indicates that requestor agrees to make results of studies using the data available to the larger scientific community.

DUO:0000020
version: 2021-02-23

collaboration required

This data use modifier indicates that the requestor must agree to collaboration with the primary study investigator(s).

DUO:0000021
version: 2021-02-23

ethics approval required

This data use modifier indicates that the requestor must provide documentation of local IRB/ERB approval.

DUO:0000022
version: 2021-02-23

geographical restriction

This data use modifier indicates that use is limited to within a specific geographic region.

DUO:0000024
version: 2021-02-23

publication moratorium

This data use modifier indicates that requestor agrees not to publish results of studies until a specific date.

DUO:0000025
version: 2021-02-23

time limit on use

This data use modifier indicates that use is approved for a specific number of months.

DUO:0000026
version: 2021-02-23

user specific restriction

This data use modifier indicates that use is limited to use by approved users.

DUO:0000027
version: 2021-02-23

project specific restriction

This data use modifier indicates that use is limited to use within an approved project.

DUO:0000028
version: 2021-02-23

institution specific restriction

This data use modifier indicates that use is limited to use within an approved institution.

DUO:0000029
version: 2021-02-23

return to database or resource

This data use modifier indicates that the requestor must return derived/enriched data to the database/resource.

DUO:0000042
version: 2021-02-23

general research use

This data use permission indicates that use is allowed for general research use for any research purpose.

DUO:0000043
version: 2021-02-23

clinical care use

This data use modifier indicates that use is allowed for clinical use and care.

DUO:0000044
version: 2021-02-23

population origins or ancestry research prohibited

This data use modifier indicates use for purposes of population, origin, or ancestry research is prohibited.

ASCENT data availability

UCL allows access to published datasets upon written application and signature of a Data Access Agreement (DAA) being in place. Applications require approval by the ASCENT Data Access Committee (DAC), who assess whether the proposed work is allowed given participant consent, as well as the scientific purpose. Requestors will be provided with a data access form upon contact with the ASCENT DAC