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WTCCC2 project controls - 1958 British Birth Cohort and National Blood Service

WTCCC2 project controls - 1958 British Birth Cohort and National Blood Service

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00000000021 3000
EGAD00000000022 3000
EGAD00000000023 1
EGAD00000000024 1
Publications Citations
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.
Nat Genet 41: 2009 1330-1334
348
The penetrance of copy number variations for schizophrenia and developmental delay.
Biol Psychiatry 75: 2014 378-385
176
CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1.
Hum Mol Genet 23: 2014 1669-1676
52
Evidence that duplications of 22q11.2 protect against schizophrenia.
Mol Psychiatry 19: 2014 37-40
74
Copy number variation in bipolar disorder.
Mol Psychiatry 21: 2016 89-93
86
Gender differences in CNV burden do not confound schizophrenia CNV associations.
Sci Rep 6: 2016 25986
5
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.
Hum Mol Genet 25: 2016 3383-3394
90
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.
Genome Med 8: 2016 76
8
Imputation of DNA Methylation Levels in the Brain Implicates a Risk Factor for Parkinson's Disease.
Genetics 204: 2016 771-781
9
Frequency of KLK3 gene deletions in the general population.
Ann Clin Biochem 54: 2017 472-480
0
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia.
Nat Commun 8: 2017 14175
45
The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability.
Nat Genet 49: 2017 1167-1173
111
Further investigations of the W-test for pairwise epistasis testing.
Wellcome Open Res 2: 2017 54
0
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.
Nat Commun 8: 2017 1892
27
Leveraging putative enhancer-promoter interactions to investigate two-way epistasis in Type 2 Diabetes GWAS.
Pac Symp Biocomput 23: 2018 548-558
1
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.
Nat Commun 9: 2018 321
48
Using Y-Chromosomal Haplogroups in Genetic Association Studies and Suggested Implications.
Genes (Basel) 9: 2018 E45
3
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.
Nat Commun 9: 2018 1340
36
SumHer better estimates the SNP heritability of complex traits from summary statistics.
Nat Genet 51: 2019 277-284
74
Genetic architecture of human thinness compared to severe obesity.
PLoS Genet 15: 2019 e1007603
35
Understanding HLA associations from SNP summary association statistics.
Sci Rep 9: 2019 1337
6
scoreInvHap: Inversion genotyping for genome-wide association studies.
PLoS Genet 15: 2019 e1008203
6
Midnolin is a confirmed genetic risk factor for Parkinson's disease.
Ann Clin Transl Neurol 6: 2019 2205-2211
5
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility.
Science 365: 2019 eaav7188
377
Identification of four novel associations for B-cell acute lymphoblastic leukaemia risk.
Nat Commun 10: 2019 5348
35
Common X-Chromosome Variants Are Associated with Parkinson Disease Risk.
Ann Neurol 90: 2021 22-34
11
Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia.
Am J Hum Genet 108: 2021 1823-1835
11
Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.
Nat Commun 12: 2021 6233
11
The immunogenetics of viral antigen response is associated with subtype-specific glioma risk and survival.
Am J Hum Genet 109: 2022 1105-1116
2