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HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

Based on the prior knowledge of involvement of the human leukocyte antigen locus in Han Chinese patients with carbamazepine-induced Stevens-Johnson syndrome, we imputed the HLA types for each case and control subject from the array of SNPs in the Human610-Quad GWAS platform (NCBI Build 36.1). We then performed a genome-wide association test which included the imputed HLA alleles as markers.

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Dataset ID Description Technology Samples
EGAD00000000059 1
Publications Citations
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.
N Engl J Med 364: 2011 1134-1143