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Complex Landscapes of Somatic Rearrangements in Human Breast Cancer Genomes

We have used massively parallel paired end sequencing strategies to reconstruct the genomic landscape of 24 breast cancer genomes, through the identification and characterization of 2166 somatically acquired genomic rearrangements. These studies have revealed considerable complexity in the patterns of structural variation, identified novel fusion genes and unveiled new insights into the complex structure of amplicons.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00000000053 Illumina Genome Analyzer II 1
Publications Citations
Complex landscapes of somatic rearrangement in human breast cancer genomes.
Nature 462: 2009 1005-1010
558