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WTCCC2 case-control study for Ulcerative Colitis

WTCCC2 project genome-wide case-control association study for Ulcerative Colitis (UC) using the 1958 British Birth Cohort and the UK National Blood Service collections as controls.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00000000021 3000
EGAD00000000023 1
EGAD00000000025 Affymetrix 6.0 2869
Publications Citations
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.
Nat Genet 41: 2009 1330-1334
Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease.
Inflamm Bowel Dis 22: 2016 20-27
Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network.
Genome Med 8: 2016 76
SumHer better estimates the SNP heritability of complex traits from summary statistics.
Nat Genet 51: 2019 277-284