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Genome-wide association scan in psoriasis

To identify novel susceptibility loci for psoriasis, we undertook a genome-wide association scan of of 594,224 SNPs in 2,622 individuals with psoriasis and 5,667 controls.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00000000021 3000
EGAD00000000022 3000
EGAD00000000023 1
EGAD00000000024 1
EGAD00010000124 Illumina_670k - Illuminus 2622
Publications Citations
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
Nat Genet 42: 2010 985-990
644
SumHer better estimates the SNP heritability of complex traits from summary statistics.
Nat Genet 51: 2019 277-284
112
The genetic history of Greenlandic-European contact.
Curr Biol 31: 2021 2214-2219.e4
8
Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine-mapping in the MHC and genomewide.
HGG Adv 3: 2022 100069
20
The Anglo-Saxon migration and the formation of the early English gene pool.
Nature 610: 2022 112-119
24
Automated machine learning for genome wide association studies.
Bioinformatics 39: 2023 btad545
2
Evidence for dynastic succession among early Celtic elites in Central Europe.
Nat Hum Behav 8: 2024 1467-1480
0
Human genetic structure in Northwest France provides new insights into West European historical demography.
Nat Commun 15: 2024 6710
0