Powerful Identification of Cis-regulatory SNPs in Human Primary Monocytes Using Allele-Specific Gene Expression

The aim of this study was to compare the power to detect associations between SNPs using cis-eQTL mapping and ASE analysis (allele specific expression).

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

3 Datasets 3 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00010000387	Cambridge control samples using a 1.2M genotyping chip from Illumina	Illumina Human 1.2M Duo custom BeadChips v1 - Genome Studio	188
EGAD00010000389	Cambridge control samples using a 24k expression array from Illumina	Illumina Human-Ref 8 v3.0 expression array	395
EGAD00010000391	Cambridge control samples using a 660K genotyping chip from Illumina	Illumina Human 660K Quad BeadChips - Illuminus	232

Publications	Citations
Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression. Almlöf JC, Lundmark P, Lundmark A, Ge B, Maouche S, Göring HH, Liljedahl U, Enström C, Brocheton J, Proust C, Godefroy T, Sambrook JG, Jolley J, Crisp-Hihn A, Foad N, Lloyd-Jones H, Stephens J, Gwilliam R, Rice CM, Hengstenberg C, Samani NJ, Erdmann J, Schunkert H, Pastinen T, Deloukas P, Goodall AH, Ouwehand WH, Cambien F, Syvänen AC. PLoS One 7: 2012 e52260	30
Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes. Almlöf JC, Lundmark P, Lundmark A, Ge B, Pastinen T, Cardiogenics Consortium, Goodall AH, Cambien F, Deloukas P, Ouwehand WH, Syvänen AC. PLoS One 9: 2014 e102612	5
Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs. Adoue V, Schiavi A, Light N, Almlöf JC, Lundmark P, Ge B, Kwan T, Caron M, Rönnblom L, Wang C, Chen SH, Goodall AH, Cambien F, Deloukas P, Ouwehand WH, Syvänen AC, Pastinen T. Mol Syst Biol 10: 2014 754	18