Whole genome sequencing in a multiplex Crohn s disease family
|Study ID||Alternative Stable ID||Type|
|EGAS00001000060||Whole Genome Sequencing|
Study Datasets 1 dataset.
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In 2009 we identified a four-generation family with over 700 members and 41 affected with Crohn's disease (CD). At the time we sequenced the exome of 6 affected individuals but did not identify any coding variants which appear to explain the high prevalence of disease. Since then we have collected DNA from a large number of additional family members, genotyped linkage arrays on the entire family to refine genomic regions shared by identity by descent and genotyped affected and unaffected ... (Show More)
|Illumina HiSeq 2000||8|