SFHS_pedigrees

Deep (>25x mean coverage) whole genome sequencing on 5-10 families drawn from the Scottish Family Health Study with four or more children.

2 Datasets 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001001214	Deep (>25x mean coverage) whole genome sequencing on 5-10 families drawn from the Scottish Family Health Study with four or more children.	Illumina HiSeq 2000	19
EGAD00001003211	Deep (>25x mean coverage) whole genome sequencing on 5-10 families drawn from the Scottish Family Health Study with four or more children.	HiSeq X Ten	57

Publications	Citations
Timing, rates and spectra of human germline mutation. Rahbari R, Wuster A, Lindsay SJ, Hardwick RJ, Alexandrov LB, Turki SA, Dominiczak A, Morris A, Porteous D, Smith B, Stratton MR, UK10K Consortium, Hurles ME. Nat Genet 48: 2016 126-133	412
Similarities and differences in patterns of germline mutation between mice and humans. Lindsay SJ, Rahbari R, Kaplanis J, Keane T, Hurles ME. Nat Commun 10: 2019 4053	86