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We propose to definitively characterise the somatic genetics of matched pair breast cancer cell lines through generation of comprehensive catalogues of somatic mutations by high coverage genome sequencing coupled with integrated transcriptomic and methylation analyses.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001000130 Illumina HiSeq 2000 22
EGAD00001002237 Illumina Genome Analyzer II Illumina HiSeq 2000 59
EGAD00001004124 Illumina HiSeq 2000 12
Publications Citations
Structural rearrangements generate cell-specific, gene-independent CRISPR-Cas9 loss of fitness effects.
Genome Biol 20: 2019 27