Study
Chordoma Exome Sequencing
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001000188 | Cancer Genomics |
Study Description
Agilent whole exome hybridisation capture will be performed on genomic DNA derived from Chordoma cancers and matched normal DNA from the same patients. Three lanes of Illumina GA sequencing will be performed on the resulting exome libraries and mapped to build 37 of the human reference genome to facilitate the identification of novel cancer genes.
Study Datasets 2 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001000119 |
Chordoma Exome Sequencing
|
Illumina Genome Analyzer II,Illumina HiSeq 2000 | 50 |
| EGAD00001000226 |
Chordoma is a rare malignant bone tumor that expresses the transcription factor T. We conducted an association study of 40 patients with chordoma and 358 ancestry-matched, unaffected individuals with replication in an independent cohort. Whole-exome and Sanger sequencing of T exons reveals a strong risk association ( allelic odds ratio (OR) = 4.9, P = 3.3x10-11, CI= 2.9-8.1) with the common (minor allelic frequency >5%) non-synonymous SNP rs2305089 in chordoma, which is exceptional in ... (Show More)
|
Illumina Genome Analyzer II,Illumina HiSeq 2000 | 18 |
Who archives the data?
