Whole-genome sequencing analysis of low-grade astrocytomas within the ICGC PedBrain Tumor Project

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001000271	Pilot study Pilocytic Astrocytoma ICGC PedBrain, whole genome sequencing of 5 tumors and matched blood	Illumina HiSeq 2000	10
EGAD00001000616	Pilocytic Astrocytoma ICGC PedBrain whole genome sequencing	Illumina HiSeq 2000	192
EGAD00001000617	Pilocytic Astrocytoma ICGC PedBrain RNA sequencing	Illumina HiSeq 2000	73

Publications	Citations
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, Gronych J, Lasitschka B, Schmidt S, Seker-Cin H, Witt H, Sultan M, Ralser M, Northcott PA, Hovestadt V, Bender S, Pfaff E, Stark S, Faury D, Schwartzentruber J, Majewski J, Weber UD, Zapatka M, Raeder B, Schlesner M, Worth CL, Bartholomae CC, von Kalle C, Imbusch CD, Radomski S, Lawerenz C, van Sluis P, Koster J, Volckmann R, Versteeg R, Lehrach H, Monoranu C, Winkler B, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, Ebinger M, Schuhmann MU, Cho YJ, Pomeroy SL, von Deimling A, Witt O, Taylor MD, Wolf S, Karajannis MA, Eberhart CG, Scheurlen W, Hasselblatt M, Ligon KL, Kieran MW, Korbel JO, Yaspo ML, Brors B, Felsberg J, Reifenberger G, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM, International Cancer Genome Consortium PedBrain Tumor Project. Nat Genet 45: 2013 927-932	477
confFuse: High-Confidence Fusion Gene Detection across Tumor Entities. Huang Z, Jones DTW, Wu Y, Lichter P, Zapatka M. Front Genet 8: 2017 137	7
Pilocytic astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response. Aichmüller CF, Iskar M, Jones DTW, Korshunov A, Radlwimmer B, Kool M, Ernst A, Pfister SM, Lichter P, Zapatka M. Neuro Oncol 22: 2020 1327-1338	8
Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma. Picard D, Felsberg J, Langini M, Stachura P, Qin N, Macas J, Reiss Y, Bartl J, Selt F, Sigaud R, Meyer FD, Stefanski A, Stühler K, Roque L, Roque R, Pandyra AA, Brozou T, Knobbe-Thomsen C, Plate KH, Roesch A, Milde T, Reifenberger G, Leprivier G, Faria CC, Remke M. Acta Neuropathol 146: 2023 551-564	2