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Egypt_Genome_Project___high_coverage_whole_genome_sequencing

All humans outside Africa are descendants of the same single exit, usually dated at 50-70 thousand years ago. However, the route taken out of Africa is still debated. The two main candidates are a northern route via Egypt and the Levant, or a southern route via Ethiopia and the Arabian Peninsula. We are generating genetic data to evaluate these two possibilities. In this study we propose to generate high-coverage sequencing data for 3 Egyptian samples.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001001380 Illumina HiSeq 2000 3
EGAD00001003295 3
Publications Citations
Tracing the route of modern humans out of Africa by using 225 human genome sequences from Ethiopians and Egyptians.
Am J Hum Genet 96: 2015 986-991
84
An integrated personal and population-based Egyptian genome reference.
Nat Commun 11: 2020 4719
18
The genomic history of the Middle East.
Cell 184: 2021 4612-4625.e14
20
Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis.
Front Immunol 13: 2022 960068
1
Modelling the demographic history of human North African genomes points to a recent soft split divergence between populations.
Genome Biol 25: 2024 201
1