DNA from colon cancer samples and matched normal samples was hybridized on Human 660W-Quad SNP arrays and sequenced in Illumina HiScanSQ.

DNA from colon cancer samples and matched normal samples was hybridized on Human 660W-Quad SNP arrays and sequenced in Illumina HiScanSQ. The objective of the study was to introduce methodology for the detection of genomic copy number alterations (CNAs) using high-throughput sequencing data. The samples in this study allow the comparison of the results from the seqCNA R package with those from other methods that detect copy number alterations (CNAs) in tumoural samples, either using SNP-array data or high-throughput sequencing data.

Type: Other
Archiver: EGA European Genome-Phenome Archive

4 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001000642	None	Illumina HiScanSQ	2
EGAD00001000643	None	Illumina HiScanSQ	2
EGAD00010000492	Cases_Human660W-Quad_v1_A	Illumina_Human660W-Quad_v1_A-Not supplied	4
EGAD00010000494	Controls_Human660W-Quad_v1_A	Illumina_Human660W-Quad_v1_A-Not supplied	4

Publications	Citations
seqCNA: an R package for DNA copy number analysis in cancer using high-throughput sequencing. Mosen-Ansorena D, Telleria N, Veganzones S, De la Orden V, Maestro ML, Aransay AM. BMC Genomics 15: 2014 178	8