Whole genome sequencing of Japanese HCCs

To determine somatic mutation profiles and substitution signatures in Japanese HCC, we performed whole genome sequencing of 31 HCCs with various epidemiological backgrounds. Somatic mutations and rearrangements were determined as previously reported. The data will be deposited to the ICGC database and is used for further comparative and integrative analyses.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

2 Datasets 3 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001001262	Unaligned bam of 31 samples derived from primary tumor	Illumina Genome Analyzer IIx Illumina HiSeq 2000	31
EGAD00001001263	Unaligned bam of 31 samples derived from blood	Illumina Genome Analyzer IIx Illumina HiSeq 2000	31

Publications	Citations
Epigenetic landscape influences the liver cancer genome architecture. Hama N, Totoki Y, Miura F, Tatsuno K, Saito-Adachi M, Nakamura H, Arai Y, Hosoda F, Urushidate T, Ohashi S, Mukai W, Hiraoka N, Aburatani H, Ito T, Shibata T. Nat Commun 9: 2018 1643	27
Advances in genomic hepatocellular carcinoma research. Huang W, Skanderup AJ, Lee CG. Gigascience 7: 2018 None	20
The Identification and Interpretation of cis-Regulatory Noncoding Mutations in Cancer. Patel MB, Wang J. High Throughput 8: 2018 E1	3