RNAseq data to study PRPF6 regulated splice forms in colon cancer cell lines
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Alternative splicing plays critical roles in differentiation, development, and cancer (Pettigrew et al., 2008; Chen and Manley, 2009). The recent identification of specific spliceosome inhibitors has generated interest in the therapeutic potential of targeting this cellular process (van Alphen et al., 2009). Using an integrated genomic approach, we have identified PRPF6, an RNA binding component of the pre-mRNA spliceosome, as an essential driver of oncogenesis in colon cancer. Importantly, ... (Show More)
|Illumina HiSeq 2000||34|