Need Help?


Whole exome sequencing of a subset of participants from the INTERVAL study.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001002221 Illumina HiSeq 2000 4502
Publications Citations
The influence of rare variants in circulating metabolic biomarkers.
PLoS Genet 16: 2020 e1008605
Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription.
Cell Metab 31: 2020 1107-1119.e12
Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila.
PLoS Biol 19: 2021 e3001255
Whole-exome sequencing identifies rare genetic variants associated with human plasma metabolites.
Am J Hum Genet 109: 2022 1038-1054
Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior.
Nat Med 28: 2022 2537-2546
Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease.
Nat Genet 56: 2024 579-584