Multisite Primary Breast Cancer
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Cancers are ecosystems of genetically related clones, competing across space and time for limited resources. To understand the clonal structure of primary breast cancer, we applied genome and targeted sequencing to 295 samples from 49 patients’ tumors. The extent of subclonal diversification varied considerably among patients and encompassed many spatial patterns, including local growth, intraductal dissemination and clonal intermixture. Landmarks of disease progression, such as acquiring ... (Show More)
|Illumina HiSeq 2000||331|