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WTCCC3_Anorexia_Nervosa

As part of the Genetic Consortium for Anorexia Nervosa (GCAN) and Wellcome Trust CaseControl Consortium 3 (WTCCC3), we have amassed the largest anorexia nervosa (AN)sample in the world (~4,000). Following the WTCCC3 GWAS, we secured funding from theKlarman Family Foundation to extend the genetic analyses to variants on the exome chip(CoreExome array). This pre-lim relates to carrying out genotyping on the CoreExome arrayon up to a maximum of 580 new samples.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00010001034 Illumina Human670-QuadCustom_v1_A 1696
EGAD00010001043 Illumina HumanCoreExome-12v1-0_A and HumanCoreExome-24v1-0_A 925
Publications Citations
Exploration of large, rare copy number variants associated with psychiatric and neurodevelopmental disorders in individuals with anorexia nervosa.
Psychiatr Genet 27: 2017 152-158
13
Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.
Mol Psychiatry 23: 2018 1169-1180
17
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.
Nat Genet 51: 2019 1207-1214
421