Study

Genotyping of additional Inflammatory Bowel Disease cases 2014

Study ID Alternative Stable ID Type
EGAS00001000924 Other

Study Description

Both internal and external funding has enabled 5000 inflammatory bowel disease cases to be whole genome sequenced (CD @4X, UC @2X). The Anderson and Barrett groups are currently generating genotypes across these samples for comparison to 4000 population controls sequenced as part of UK10K. The UK10K project has shown that imputing sequenced genetic variation into previously GWASed samples greatly increases power to detect association. Given that our study has been designed to detect association to low frequency variation (0.5% and above) these gains in power are especially important. Overall, the UKIBDGC has GWAS data for around 1800 CD samples (Affy 500K) and 3000 UC samples (Affy6), though some of these samples have also been whole genome sequenced. Here, we apply to get all remaining non-GWAS and non-WGS IBD cases in the UKIBDGC (N=X) genotyped genotyped on the Illumina Core Exome Array

Study Datasets 2 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00010001157
Genotyping of additional Inflammatory Bowel Disease cases - 2014 (QC pass samples)
Illumina Human Core Exome 12v1-1_a 9247
EGAD00010001158
Genotyping of additional Inflammatory Bowel Disease cases - 2014 (all samples)
Illumina Human Core Exome 12v1-1_a 11767

Who archives the data?

There are no publications available