PREDICT Whole Genomes
|Study ID||Alternative Stable ID||Type|
Study Datasets 2 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Clear cell renal cancer is characterized by near-universal loss of the short arm of chromosome 3 (3p). This event arises through unknown mechanisms, but critically results in the loss of several tumor suppressor genes. We analyzed whole genomes from 95 biopsies across 33 patients with clear cell renal cancer (ccRCC) recruited into the Renal TRACERx study. We find novel hotspots of point mutations in the 5'-UTR of TERT, targeting a MYC-MAX repressor, that result in telomere lengthening. The most ... (Show More)
|HiSeq X Ten||164|
We investigated the somatic genetic basis of Wilms’ tumour and found complex phylogenetic relations between tumours.
|HiSeq X Ten||203|