BLUEPRINT Gene expression analysis during human B-cell differentiation using the Affymetrix Human Genome U219 Array
We performed gene expression analysis using the Affymetrix Human Genome U219 Array of 9 subpopulations covering the complete B-cell maturation program: hematopoietic progenitor cells (HPC); pre-B-I cells (preB1C); pre-B-II cells (preB2C); naive B cells from peripheral blood (naiBC); naive B cells from tonsil (t-naiBC); germinal center B cells (gcBC); plasma cells from tonsil (t-PC); memory B cells from peripheral blood (memBC) and plasma cells from bone marrow (bm-PC). All the samples were isolated from healthy donors and, with the exception of bm-PC (only 1 replicate), we used 3 to 11 biological replicates of each subtype.
- Type: Other
- Archiver: EGA European Genome-Phenome Archive
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00010000718 | 42 |
Publications | Citations |
---|---|
Whole-genome fingerprint of the DNA methylome during human B cell differentiation.
Nat Genet 47: 2015 746-756 |
176 |
The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome.
Nat Cancer 1: 2020 1066-1081 |
19 |