Anaplastic oligodendroglioma exome and RNA sequencing data
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Anaplastic oligodendrogliomas (AOs) are rare primary brain tumors which are generally incurable, with heterogeneous prognosis and few treatment targets identified. Most oligodendrogliomas have chromosome 1p/19q co-deletion and IDH mutation. We analyzed 51 AOs by whole-exome sequencing, identifying previously reported frequent somatic mutations in CIC and FUBP1. We also identified recurrent mutations in TCF12 and in an additional series of 83 AO. Overall 7.5% of AO are mutated for TCF12, which ... (Show More)
|Illumina HiSeq 2000||102|